Erectile dysfunction (impotence) is the incapability to get and keep an erection firm enough for sex. Having erection trouble from time to time isn’t necessarily a cause for concern. If erectile dysfunction is a continuing issue, though, it can cause stress, touch your self-confidence and contribute to association problems. Problems getting or keeping an erection can also be a sign of an underlying health disorder that needs treatment and a risk issue for heart disease. Avanafil which may be taken with or without food, is a “phosphodiesterase type 5” or PDE 5 inhibitor that increases blood flow to the penis. During sexual stimulation, the body foodstuffs cyclic GMP or cGMP. This substance causes blood vessel enlargement in the penis and, henceforth, increased blood flow to the penis, subsequent in an erection. cGMP is broken down by PDE 5. Therefore, when PDE 5 is congested or reserved, the quantity of cGMP in the penis upsurges, leading to augmented blood flow and an erection.
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